Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/52733
Title: Palladium-catalyzed synthesis of 6-aryl dopamine derivatives
Authors: Calcaterra Andrea
Fernández García Santiago
Marrone Federico
Bernini, Roberta 
Fabrizi Giancarlo
Goggiamani Antonella
Iazzetti Antonia
Journal: CATALYSTS 
Issue Date: 2024
Abstract: 
Dopamine is a key neurotransmitter involved in a series of biologically relevant processes
and its derivatives have sparked significant interest as intriguing synthetic targets. This class of
compounds is indeed not only considerable for the potential biological activities but is also promising
for diverse applications in material science. In light of this, our research was focused on the
synthesis of 6-aryldopamine derivatives starting from 4-(2-aminoethyl)phenol through a sequential protocol, whose main steps are hydroxylation, halogenation, and Suzuki cross-coupling. Our method demonstrated versatility, efficiency, and compatibility with various functional groups, including aldehydes, ketones, esters, ethers, and fluorine.
URI: http://hdl.handle.net/2067/52733
ISSN: 2073-4344
DOI: 10.3390/catal14070401
Rights: Attribution-NonCommercial-NoDerivatives 4.0 International
Appears in Collections:A1. Articolo in rivista

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