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http://hdl.handle.net/2067/51852
Titolo: | Biosynthesis of Novel Ascorbic Acid Esters and Their Encapsulation in Lignin Nanoparticles as Carriers and Stabilizing Systems | Autori: | Capecchi, Eliana Piccinino, Davide Nascimben, Chiara Tomaino, Elisabetta Ceccotti Vlas, Natalia Gabellone, Sofia Saladino, Raffaele |
Rivista: | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | Data pubblicazione: | 2023 | Abstract: | A dual-target strategy was designed for the application of lignin nanoparticles in the lipase mediated biosynthesis of novel 3-O-ethyl-L-ascorbyl-6-ferulate and 3-O-ethyl-L-ascorbyl-6-palmitate and in their successive solvent-shift encapsulation in order to improve stability and antioxidant activity against temperature and pH-dependent degradation. The loaded lignin nanoparticles were fully characterized in terms of kinetic release, radical scavenging activity and stability under pH 3 and thermal stress (60 °C), showing improved antioxidant activity and high efficacy in the protection of ascorbic acid esters from degradation. |
URI: | http://hdl.handle.net/2067/51852 | ISSN: | 1422-0067 | DOI: | 10.3390/ijms24109044 | Diritti: | CC0 1.0 Universal |
È visualizzato nelle collezioni: | A1. Articolo in rivista |
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