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Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/48965
DC FieldValueLanguage
dc.contributor.authorDe Marchi, Elisait
dc.contributor.authorBotta, Lorenzoit
dc.contributor.authorBizzarri, Bruno Mattiait
dc.contributor.authorSaladino, Raffaeleit
dc.date.accessioned2023-01-25T08:29:14Z-
dc.date.available2023-01-25T08:29:14Z-
dc.date.issued2022it
dc.identifier.issn1420-3049it
dc.identifier.urihttp://hdl.handle.net/2067/48965-
dc.description.abstractQuinol derivatives of estrogens are effective pro-drugs in steroid replacement therapy. Here, we report that these compounds can be synthesized in one-pot conditions and high yield by blue LED-driven photo-oxygenation of parent estrogens. The oxidation was performed in buffer and eco-certified 2-methyltetrahydrofuran as the two-liquid-phase reaction solvent, and in the presence of meso-tetraphenyl porphyrin as the photosensitizer. Two steroidal prodrugs 10β, 17β-dihydroxyestra-1,4-dien-3-one (DHED) and 10β-Hydroxyestra-1,4-diene-3,17-dione (HEDD) were obtained with high yield and selectivity.it
dc.format.mediumELETTRONICOit
dc.language.isoengit
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleA Green Blue LED-Driven Two-Liquid-Phase One-Pot Procedure for the Synthesis of Estrogen-Related Quinol Prodrugsit
dc.typearticle*
dc.identifier.doi10.3390/molecules27248961it
dc.identifier.pmid36558094it
dc.identifier.scopus2-s2.0-85144891396it
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/85144891396it
dc.relation.journalMOLECULESit
dc.relation.firstpage8961it
dc.relation.volume27it
dc.relation.issue24it
dc.description.numberofauthors4it
dc.description.internationalnoit
dc.contributor.countryITAit
dc.type.refereeREF_1it
dc.type.miur262*
item.fulltextWith Fulltext-
item.openairetypearticle-
item.cerifentitytypePublications-
item.grantfulltextopen-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.journal.journalissn1420-3049-
crisitem.journal.anceE184319-
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