Please use this identifier to cite or link to this item:
http://hdl.handle.net/2067/48325
Title: | Transport of cationic liposomes in a human blood brain barrier model: Role of the stereochemistry of the gemini amphiphile on liposome biological features | Authors: | Buonocore, Francesco Beatrice Simonis D. Vignone O. Gonzalez Paz E. Donati M.L. Falchetti C. Bombelli A. Cellucci G. Auciello I. Fini L. Galantini R.Z.R. Syeda M. Mazzonna M.P. Mongiardi F. Ceccacci A. Di Marco G. Mancini |
Journal: | JOURNAL OF COLLOID AND INTERFACE SCIENCE | Issue Date: | 2022 | Abstract: | Hypothesis: The positive charge on liposome surface is known to promote the crossing of the Blood brain barrier (BBB). However, when diastereomeric cationic gemini amphiphiles are among lipid membrane components, also the stereochemistry may affect the permeability of the vesicle across the BBB. Experiments: Liposomes featuring cationic diasteromeric gemini amphiphiles were formulated, characterized, and their interaction with cell culture models of BBB investigated. |
URI: | http://hdl.handle.net/2067/48325 | ISSN: | 0021-9797 | DOI: | https://doi.org/10.1016/j.jcis.2022.07.025 | Rights: | Attribution-NonCommercial-NoDerivatives 4.0 International |
Appears in Collections: | A1. Articolo in rivista |
Files in This Item:
File | Description | Size | Format | Existing users please |
---|---|---|---|---|
PreproofLiposome.pdf | Pre-proof articolo accettato | 10 MB | Adobe PDF | Request a copy |
Page view(s)
67
Last Week
0
0
Last month
0
0
checked on Mar 27, 2024
Download(s)
3
checked on Mar 27, 2024
Google ScholarTM
Check
Altmetric
This item is licensed under a Creative Commons License