Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/47547
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dc.contributor.authorBuonocore, Francescoit
dc.contributor.authorNuñez-Ortiz, Noeliait
dc.contributor.authorPicchietti, Simonait
dc.contributor.authorRandelli, Elisait
dc.contributor.authorStocchi, Valentinait
dc.contributor.authorGuerra, Laurait
dc.contributor.authorToffan, Annait
dc.contributor.authorPascoli, Francescoit
dc.contributor.authorFausto, Anna Mariait
dc.contributor.authorMazzini, Massimoit
dc.contributor.authorScapigliati, Giuseppeit
dc.date.accessioned2022-04-17T18:10:00Z-
dc.date.available2022-04-17T18:10:00Z-
dc.date.issued2019it
dc.identifier.issn1050-4648it
dc.identifier.urihttp://hdl.handle.net/2067/47547-
dc.description.abstractThis review summarizes the available knowledge on the immune defences of European sea bass against antigenic preparations derived from the viral encephalopathy and retinopathy virus (betanodavirus), which represents a major threat to the health of this fish species. The nodavirus is widely present and differentiates into several strains that infect invertebrates (in insects, alphanodavirus) and teleost fish, and thus may represent a great problem for farmed fish species. Many efforts have been directed to discovering new immunizations to induce protection in sea bass, especially at young stages, and these efforts have included employing diverse betanodavirus strains, antigen preparation, vaccination routes, and the addition of adjuvants and/or immunostimulants. The obtained results showed that inactivated preparations of betanodavirus that were administered intraperitoneally may induce both immune recognition and protection. Attempts at performing mucosal immunization by immersion and/or oral administration, which is a vaccination route that is highly preferred for sea bass, have shown intriguing results, and more studies are necessary for its improvement. Overall, the objective of identifying a reliable vaccine that also cross-protects against different genotypes or reassortant viruses for use in European sea bass against betanodavirus appears to be an attainable goal in the near future.it
dc.format.mediumSTAMPAit
dc.language.isoengit
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleVaccination and immune responses of European sea bass (Dicentrarchus labrax L.) against betanodavirusit
dc.typearticle*
dc.identifier.doi10.1016/j.fsi.2017.11.039it
dc.identifier.pmid29175472it
dc.identifier.scopus2-s2.0-85034834482it
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S1050464817307167it
dc.relation.journalFISH AND SHELLFISH IMMUNOLOGYit
dc.relation.firstpage78it
dc.relation.lastpage84it
dc.relation.numberofpages7it
dc.relation.volume85it
dc.subject.scientificsectorBIO/10it
dc.description.numberofauthors11it
dc.description.internationalnoit
dc.contributor.countryITAit
dc.type.refereeREF_1it
dc.type.miur262*
item.fulltextWith Fulltext-
item.openairetypearticle-
item.cerifentitytypePublications-
item.grantfulltextrestricted-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.journal.journalissn1050-4648-
crisitem.journal.anceE064933-
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