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http://hdl.handle.net/2067/46178
Title: | Perspectives on Populus spp. (Salicaceae) bud extracts as antioxidant and anti-inflammatory agents | Authors: | Pannucci, Elisa D'Eliseo, Donatella Ieri, Francesca Romani, Annalisa Santi, Luca Bernini, Roberta Sabatti, Maurizio Velotti, Francesca Romana |
Journal: | NATURAL PRODUCT RESEARCH | Issue Date: | 2021 | Abstract: | Hydroalcoholic extracts obtained from buds of P. nigra, P. deltoides and P. trichocarpa were characterized by HPLC-DAD-MS analysis and subsequently evaluated in vitro for their antioxidant and anti-inflammatory activities. ABTS and DPPH assays evidenced that P. nigra showed the best antioxidant activity in line with its highest total phenolic content. The analysis of the anti-inflammatory activity clearly demonstrated that all extracts suppressed the production of key pro-inflammatory cytokines (IL-6, Il-1β and TNF-α) and HMGB1 inflammatory danger signal. These results show antioxidant and critical anti-inflammatory activities mediated by the extracts, emphasising their potentiality as therapeutic agents. |
URI: | http://hdl.handle.net/2067/46178 | ISSN: | 1478-6427 | DOI: | 10.1080/14786419.2021.1896512 | Rights: | CC0 1.0 Universal |
Appears in Collections: | A1. Articolo in rivista |
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