Please use this identifier to cite or link to this item:
http://hdl.handle.net/2067/42933
Title: | Homogentisic Acid and Gentisic Acid Biosynthesized Pyomelanin Mimics: Structural Characterization and Antioxidant Activity | Authors: | Al Khatib, Maher Costa, Jessica Spinelli, Daniele Capecchi, Eliana Saladino, Raffaele Baratto, Maria Camilla Pogni, Rebecca |
Journal: | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | Issue Date: | 2021 | Abstract: | Pyomelanin mimics from homogentisic acid (HGA) and gentisic acid (GA) were biosynthesized by the oxidative enzyme T. versicolor laccase at physiological pH to obtain water soluble melanins. The pigments show brown-black color, broad band visible light absorption, a persistent paramagnetism and high antioxidant activity. The EPR approach shows that at least two different radical species are present in both cases, contributing to the paramagnetism of the samples. This achievement can also shed light on the composition of the ochronotic pigment in the Alkaptonuria disease. On the other hand, these soluble pyomelanin mimics, sharing physico-chemical properties with eumelanin, can represent a suitable alternative to replace the insoluble melanin pigment in biotechnological applications. |
URI: | http://hdl.handle.net/2067/42933 | ISSN: | 1661-6596 | DOI: | 10.3390/ijms22041739 | Rights: | CC0 1.0 Universal |
Appears in Collections: | A1. Articolo in rivista |
Files in This Item:
File | Description | Size | Format | Existing users please |
---|---|---|---|---|
Pogni_ijms-22-01739 2021.pdf | 2.51 MB | Adobe PDF | Request a copy |
SCOPUSTM
Citations
20
7
Last Week
0
0
Last month
1
1
checked on Apr 14, 2024
Page view(s)
36
Last Week
0
0
Last month
1
1
checked on Apr 17, 2024
Download(s)
4
checked on Apr 17, 2024
Google ScholarTM
Check
Altmetric
This item is licensed under a Creative Commons License