Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/1734
Title: New lipophilic piceatannol derivatives exhibiting antioxidant activity prepared by aromatic hydroxylation with 2-iodoxybenzoic acid (IBX)
Authors: Bernini, Roberta
Barontini, Maurizio
Spatafora, Carmela
Keywords: Aromatic hydroxylation;2-Iodoxybenzoic acid (IBX);Lipophilic piceatannol;Lipophilic antioxidants
Issue Date: 2009
Publisher: MPDI
Source: Bernini R., Barontini M., Spatafora C. 2009. New lipophilic piceatannol derivatives exhibiting antioxidant activity prepared by aromatic hydroxylation with 2-iodoxybenzoic acid (IBX). "Molecules" 14: 4669-4681
Abstract: 
Piceatannol (E-3,5,3’,4’ tetrahydroxystilbene) is a phytoalexin synthesized in grapes in response to stress conditions. It exhibits strong antioxidant and antileukaemic activities due to the presence of the catechol moiety. To modify some physical properties like solubility, and miscibility in non-aqueous media some new previously unreported piceatannol derivatives having lipophilic chains on the A-ring were prepared in good yields by a simple and efficient procedure. The key step was a chemo- and regioselective aromatic hydroxylation with 2-iodoxybenzoic acid (IBX). The new compounds showed antioxidant activity and seemed promising for possible applications as multifunctional emulsifiers in food, cosmetic and pharmaceutical fields.
Description: 
L'articolo è disponibile sul sito dell'editore: http://www.mdpi.com
URI: http://hdl.handle.net/2067/1734
ISSN: 1420-3049
DOI: 10.3390/molecules14114669
Appears in Collections:DABAC - Archivio della produzione scientifica

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