Please use this identifier to cite or link to this item:
http://hdl.handle.net/2067/1720| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Palitti, Fabrizio | - |
| dc.contributor.author | Pichierri, Pietro | - |
| dc.contributor.author | Franchitto, Annapaola | - |
| dc.contributor.author | Proietti De Santis, Luca | - |
| dc.contributor.author | Mosesso, Pasquale | - |
| dc.date.accessioned | 2011-03-25T15:57:17Z | - |
| dc.date.available | 2011-03-25T15:57:17Z | - |
| dc.date.issued | 1999 | - |
| dc.identifier.citation | Palitti, F. et al. 1999. Chromosome radiosensitivity in human G2 lymphocytes and cell cycle progression. "International Journal of Radiation Biology" 75(5): 621-627 | en |
| dc.identifier.issn | 0955-3002 | - |
| dc.identifier.uri | http://hdl.handle.net/2067/1720 | - |
| dc.description | L'articolo è disponibile sul sito dell'editore: http://informahealthcare.com | it |
| dc.description.abstract | PURPOSE: To investigate the possibility that the differential G2-phase radiosensitivity of human peripheral blood lymphocytes, found in normal individuals using the 'G2-phase chromosome radiosensitivity assay', could be attributed to heterogeneity in cellular progression to mitosis rather than differences in radiosensitivity. MATERIALS AND METHODS: Human peripheral blood lymphocytes, from four different donors, were exposed to 50 cGy X-rays and sampled at different times. The progression of cells into mitosis was monitored by 5-bromo 2'-deoxyuridine (BrdUrd) incorporation. RESULTS: The heterogeneous G2-phase chromosome radiosensitivity among different donors was abolished when homogeneous G2-phase cell populations were scored; they contained similar frequencies of cells in early or late G2-phase. CONCLUSIONS: The heterogeneous G2-phase chromosome radiosensitivity, usually found in different normal donors, is caused by the analysis of different cell populations rather than reflecting intrinsic differences in radiosensitivity | en |
| dc.language.iso | en | en |
| dc.publisher | Informa Healthcare | en |
| dc.title | Chromosome radiosensitivity in human G2 lymphocytes and cell cycle progression | en |
| dc.type | Article | en |
| local.message.claim | 2022-03-15T13:22:47.127+0100|||rp00191|||submit_approve|||dc_contributor_author|||None | * |
| item.fulltext | With Fulltext | - |
| item.openairetype | Article | - |
| item.cerifentitytype | Publications | - |
| item.grantfulltext | open | - |
| item.languageiso639-1 | en | - |
| item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
| Appears in Collections: | DABAC - Archivio della produzione scientifica | |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| ABSTRACT.pdf | 92.15 kB | Adobe PDF | View/Open |
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