Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/1695
Title: Relationship between DNA Repair and Formation of Sister Chromatid Exchanges and Chromatid Aberrations under the Influence of Poly(ADP-Ribose) Polymerase Inhibition by 3-Aminobenzamide
Authors: Filippi, Silvia
Palitti, Fabrizio
Martínez-López, Wilner
Natarajan, Adayapalam T.
Keywords: SCE;3AB;DNA Repair
Issue Date: 2010
Publisher: Karger
Source: Filippi, S. et al. 2010. Relationship between DNA Repair and Formation of Sister Chromatid Exchanges and Chromatid Aberrations under the Influence of Poly(ADP-Ribose) Polymerase Inhibition by 3-Aminobenzamide. "Cytogenetic and Genome Research" 128(1-3): 118-23
Abstract: 
The mechanisms of formation of sister chromatid exchanges (SCEs) and chromosome aberrations following inhibition of poly(ADP-ribose) polymerase by 3-aminobenzamide were studied in Chinese hamster ovary cell lines deficient in different repair pathways. The results confirm earlier findings that (a) the 'spontaneous' SCEs are formed due to the incorporated BrdU in the DNA, (b) 'spontaneous' and induced SCEs originate from different mechanisms, and (c) SCEs and chromatid exchanges are formed by different pathways.
Description: 
L'articolo é disponibile sul sito dell'editore: http://www.karger.com
URI: http://hdl.handle.net/2067/1695
ISSN: 1424-8581
DOI: 10.1159/000293820
Appears in Collections:DABAC - Archivio della produzione scientifica

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