Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/1615
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dc.contributor.authorBongiorni, Silvia-
dc.contributor.authorPugnali, Margherita-
dc.contributor.authorVolpi, Silvia-
dc.contributor.authorBizzaro, Davide-
dc.contributor.authorSingh, Prim B.-
dc.contributor.authorPrantera, Giorgio-
dc.date.accessioned2011-03-23T16:37:09Z-
dc.date.available2011-03-23T16:37:09Z-
dc.date.issued2009-
dc.identifier.citationBongiorni, S. et al. 2009. Epigenetic Marks For Chromosome Imprinting During Spermatogenesis In Coccids. "Chromosoma" 118(4): 501-512en
dc.identifier.issn0009-5915-
dc.identifier.urihttp://hdl.handle.net/2067/1615-
dc.descriptionL'articolo è disponibile sul sito dell'editore: http://www.springerlink.comit
dc.description.abstractThe establishment of sex-specific epigenetic marks during gametogenesis is one of the key feature of genomic imprinting. By immunocytological analysis, we thoroughly characterized the chromatin remodeling events that take place during gametogenesis in the mealybug Planococcus citri, in which an entire haploid set of (imprinted) chromosomes undergoes facultative heterochromatinization in male embryos. Building on our previous work, we have investigated the interplay of several epigenetic marks in the regulation of this genome-wide phenomenon. We characterized the germline patterns of histone modifications, Me(3)K9H3, Me(2)K9H3, and Me (3)K20H4, and of heterochromatic proteins, PCHET2 (HP1-like) and HP2-like during male and female gametogenesis. We found that at all stages in oogenesis chromatin is devoid of any detectable epigenetic marks. On the other hand, spermatogenesis is accompanied by a complex pattern of redistribution of epigenetic marks from euchromatin to heterochromatin, and vice versa. At the end of spermatogenesis, sperm heads are decorated by all the molecules we tested, except for PCHET2. However, only Me(3)K9H3 and Me(2)K9H3 are still detectable in the male pronucleus. We suggest that the histone H3 lysine 9 methylation is the signal used to establish the malespecific imprinting on the paternal genome, thus allowing it to be distinguished from the maternal genome in the developing embryo.en
dc.language.isoenen
dc.publisherSpringer Verlagen
dc.subjectGenomic imprintingen
dc.subjectHistone modificationsen
dc.subjectSpermatogenesisen
dc.subjectHP1en
dc.titleEpigenetic Marks For Chromosome Imprinting During Spermatogenesis In Coccidsen
dc.typeArticleen
local.message.claim2021-01-12T18:33:27.996+0100|||rp00220|||submit_approve|||dc_contributor_author|||None*
item.grantfulltextopen-
item.cerifentitytypePublications-
item.fulltextWith Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeArticle-
item.languageiso639-1en-
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