Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/1571
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dc.contributor.authorBernini, Roberta-
dc.contributor.authorCrisante, Fernanda-
dc.contributor.authorMerendino, Nicolò-
dc.contributor.authorMolinari, Romina-
dc.contributor.authorSoldatelli, Maria Chiara-
dc.contributor.authorVelotti, Francesca Romana-
dc.date.accessioned2011-03-22T16:29:26Z-
dc.date.available2011-03-22T16:29:26Z-
dc.date.issued2010-
dc.identifier.citationBernini, R. et al. 2010 Synthesis of a novel ester of hydroxytyrosol and lipoic acid exhibiting an antiproliferative effect on human colon cancer HT-29 cells. In: Ageorges, A. et al. (a cura di). XXV Th International Conference on Polyphenols. Polyphenols Communications 2010. (Montpellier, France 24-27 August). 1: 98-99en
dc.identifier.uri978-2-7380-1282-1-
dc.identifier.urihttp://hdl.handle.net/2067/1571-
dc.description.abstractA novel hydroxytyrosol-lipoic acid derivative has been synthesized. Key steps are an esterification reaction between tyrosol and -lipoic acid derivatives and a regioselective aromatic hydroxylation of the monohydroxylated ester performed by 2-iodoxybenzoic acid (IBX) followed by an in situ reduction with sodium dithionite (Na2S2O4). The novel ester exhibited an antiproliferative effect on the human colorectal adenocarcinoma HT-29 cell line significantly more potent than its parent compoundsen
dc.language.isoenen
dc.publisherImprim Verten
dc.subjectHydroxytyrosolen
dc.subjectLipoic aciden
dc.subjectNew esteren
dc.subjectAntiproliferative effecten
dc.subjectHT-29 cellsen
dc.titleSynthesis of a novel ester of hydroxytyrosol and lipoic acid exhibiting an antiproliferative effect on human colon cancer HT-29 cellsen
dc.typeConference Proceedingsen
local.message.claim2021-11-08T15:56:29.902+0100|||rp00176|||submit_approve|||dc_contributor_author|||None*
item.fulltextWith Fulltext-
item.openairetypeConference Proceedings-
item.cerifentitytypePublications-
item.grantfulltextopen-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
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