Please use this identifier to cite or link to this item:
http://hdl.handle.net/2067/1562
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Picchietti, Simona | - |
dc.contributor.author | Fausto, Anna Maria | - |
dc.contributor.author | Randelli, Elisa | - |
dc.contributor.author | Carnevali, Oliana | - |
dc.contributor.author | Taddei, Anna Rita | - |
dc.contributor.author | Buonocore, Francesco | - |
dc.contributor.author | Scapigliati, Giuseppe | - |
dc.contributor.author | Abelli, Luigi | - |
dc.date.accessioned | 2011-03-22T15:04:01Z | - |
dc.date.available | 2011-03-22T15:04:01Z | - |
dc.date.issued | 2009 | - |
dc.identifier.citation | Picchietti, S. et al. 2009. Early treatment with Lactobacillus delbrueckii strain induces an increase in intestinal T-cells and granulocytes and modulates immune-related genes of larval Dicentrarchus labrax (L.). "Fish and Shellfish Immunology" 26 (3): 368-376. | it |
dc.identifier.issn | 1050-4648 | - |
dc.identifier.uri | http://hdl.handle.net/2067/1562 | - |
dc.description | L'articolo è disponibile sul sito dell'editore http://www.sciencedirect.com/ | it |
dc.description.abstract | Lactobacillus delbrueckii ssp. delbrueckii (AS13B), isolated from the gut of adult Dicentrarchus labrax, was administered live to developing sea bass using rotifers and Artemia as live carriers. Immune-related gene transcripts were quantified in post-larvae at day 70 post-hatch (ph) and histology, electron microscopy and immunocytochemistry of the intestinal tissue were performed at day 74 ph. Since the probiotic was orally administered the studies were focused on intestinal immunity. In treated fish gut integrity was unaffected, while the density of T-cells and acidophilic granulocytes in the intestinal mucosa was significantly higher than in controls. Probiotic-induced increases in intestinal T-cells and total body TcR-beta transcripts are first reported in fish. Significantly lower IL-1beta transcripts and a trend towards lower IL-10, Cox-2 and TGF-beta transcription were found in the treated group. Evidence is provided that early feeding with probiotic-supplemented diet stimulated the larval gut immune system and lowered transcription of key pro-inflammatory genes. | it |
dc.language.iso | en | it |
dc.publisher | Elsevier | it |
dc.subject | Lactobacillus delbrueckii delbrueckii | it |
dc.subject | Probiotics | it |
dc.subject | Dicentrarchus labrax | it |
dc.subject | GALT | it |
dc.subject | Larval immunity | it |
dc.subject | T-cells | it |
dc.subject | Cytokines | it |
dc.title | Early treatment with Lactobacillus delbrueckii strain induces rise in intestinal T cells and granulocytes and modulates immune related genes of larval Dicentrarchus labrax (L.) | it |
dc.type | Article | it |
dc.identifier.doi | 10.1016/j.fsi.2008.10.008 | it |
item.fulltext | With Fulltext | - |
item.openairetype | Article | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
Appears in Collections: | DISA - Archivio della produzione scientifica |
Files in This Item:
File | Description | Size | Format | |
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FSI 2009.pdf | 72.89 kB | Adobe PDF | View/Open |
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