Please use this identifier to cite or link to this item:
Title: Interleukin 18 in the CNS
Authors: Alboni, Silvia
Cervia, Davide
Sugama, Shuei
Conti, Bruno
Issue Date: 2010
Publisher: BioMed Central
Source: Alboni, S. et al. 2010. Interleukin 18 in the CNS. "Journal of Neuroinflammation" 7:9
Interleukin (IL)-18 is cytokine isolated as an important modulator of immune responses and subsequently shown to be pleiotropic. IL-18 and its receptors are expressed in the central nervous system (CNS) where they participate in neuroinflammatory/neurodegenerative processes but also influence homeostasis and behaviour. Work on IL-18 null mice, the localization of the IL-18 receptor complex in neurons and the neuronal expression of decoy isoforms of the receptor subunits are beginning to reveal the complexity and the significance of the IL-18 system in the CNS. This review summarizes current knowledge on the central role of IL-18 in health and disease.
L'articolo è disponibile sul sito dell'editore
ISSN: 1742-2094
DOI: 10.1186/1742-2094-7-9
Appears in Collections:DISA - Archivio della produzione scientifica

Files in This Item:
File Description SizeFormat
Alboni et al 2010 J Neuroinflammation 1.pdf137.97 kBAdobe PDFView/Open
Show full item record

Page view(s)

Last Week
Last month
checked on Dec 4, 2020


checked on Dec 4, 2020

Google ScholarTM



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.