Interaction of the anticancer p28 peptide with p53-DBD as studied by fluorescence, FRET, docking and MD simulations
Author(s)
Date Issued
2019
Type
article
Volume
1863
Issue
2
Start Page
342-350
End Page
350
Abstract
The p28 peptide, derived from the blue copper protein Azurin, exerts an anticancer action due to interaction with the tumor suppressor p53, likely interfering with its down-regulators. Knowledge of both the kinetics and topological details of the interaction, could greatly help to understand the peptide anticancer mechanism.
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BBA19.pdf
Size
1.95 MB
Format
Adobe PDF
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