Novel cDNAs encoding salivary proteins from the malaria vector Anopheles gambiae
Author(s)
Lanfrancotti, Alessandra
Lombardo, Fabrizio
Santolamazza, Federica
Veneri, Massimiliano
Date Issued
2002
Type
article
Volume
517
Issue
1-3
Start Page
67
End Page
71
Journal
Abstract
Several genes encoding salivary components of the mosquito Anopheles gambiae were identified using a selective trapping approach. Among these, five corresponded to genes expressed specifically in female glands and their role may possibly be linked to blood-feeding. Our collection included a fourth member of the D7 protein family and two polypeptides that showed weak similarity to anti-coagulants from distantly related species. Moreover, we identified two additional members of a novel group of proteins that we named glandins. The isolation of tissue-specific genes represents a first step toward a deeper molecular analysis of mosquito salivary secretions.