Stimulation of gut immune system by early administration of probiotic strains in dicentrarchus labrax and sparus aurata
Author(s)
Abelli, Luigi
Randelli, Elisa
Picchietti, Simona
Carnevali, Oliana
Date Issued
2009
Type
Article
Abstract
Early feeding (started during gut metamorphosis and establishment of the
hypothalamic–pituitary–interrenal axis) with probiotic-supplemented diets, besides
modifying the intestinal microflora, evoked profound effects on the physiology of fish
larvae. Using rotifers and Artemia as living vectors, the autochthonous bacterium Lactobacillus
delbrueckii delbrueckii or a multispecies probiotic formulation (autochthonous
Lactobacillus fructivorans + Lactobacillus plantarum from human feces) were orally administered
to sea bass and gilthead sea bream larvae, respectively. The treatments
enhanced larval rearing (significantly increased body weight, decreased cortisol levels,
and improved stress response compared with controls) and the immune system. In sea
bass, the probiotic raised intestinal T cells, in keeping with increased total body TcR-β
transcripts, and increased acidophilic granulocytes concomitant to lower transcription
of pro-inflammatory genes (IL-1-β, TGF-β, IL-10, Cox-2). In sea bream, the multispecies
probiotic formulation raised intestinal immunoglobulin (Ig+) cells and acidophilic granulocytesmainly
belonging to theMAbG7+ phagocytic population. These results point to
stimulatory actions of probiotics on the gut immune system that are devoid of harmful
effects and that correlate with improvement of fry survival.
Additional information
L'articolo è disponibile sul sito dell'editore http://onlinelibrary.wiley.com/
Citation
Abelli, L. et al. 2009. Stimulation of gut immune system by early administration of probiotic strains in dicentrarchus labrax and sparus aurata. "Annals of the New York Academy of Science" 1163: 340-342
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