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  5. Phenolic-rich extracts from circular economy: chemical profile and activity against filamentous fungi and dermatophytes

Phenolic-rich extracts from circular economy: chemical profile and activity against filamentous fungi and dermatophytes

Author(s)
Lombardi, Andrea
Campo, Margherita
Vignolini, Pamela
Papalini, Marco
Pizzetti, Mirco
more
Date Issued
2023
Type
article
Volume
28
Issue
11
DOI
doi.org/10.3390/molecules28114374
Journal
MOLECULES  
Abstract
Fungal infections represent a relevant issue in agri-food and biomedical fields because they could compromise quality of food and humans’ health. Natural extracts represent a safe alternative to synthetic fungicides and in the green chemistry and circular economy scenario, agro-industrial wastes and by-products offer an eco-friendly source of bioactive natural compounds. In this paper, phenolic rich extracts from Olea europaea L. de-oiled pomace, Castanea sativa Mill. wood, Punica granatum L. peel, and Vitis vinifera L. pomace and seeds were characterized by HPLC-MS-DAD analysis. Finally, these extracts were tested as antimicrobial agents against pathogenic filamentous fungi and dermato phytes such as Aspergillus brasiliensis, Alternaria sp., Rhizopus stolonifer, and Trichophyton interdigitale. The experimental results evidenced that all extracts exhibited a significant growth inhibition for Trichophyton interdigitale. Punica granatum L., Castanea sativa Mill., and Vitis vinifera L. extracts showed a high activity against Alternaria sp. and Rhizopus stolonifer. These data are promising for the potential applications of some of these extracts as antifungal agents in the food and biomedical fields.
Subjects

Phenolic-rich extract...

Circular economy

Green chemistry

Antifungal activity

Filamentous fungi

Dermatophytes

Handle
http://hdl.handle.net/2067/50896
File(s)
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Molecules 2023_28_4374.pdf

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4.65 MB

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Adobe PDF

Checksum (MD5)

4b5bdadea603a0534c07175194a7b81c

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