Furan carcinogenicity: DNA binding and genotoxicity of furan in rats in vivo
Author(s)
Date Issued
2012
Type
article
Volume
56
Issue
9
Start Page
1363-74
End Page
1374
Abstract
Furan is a potent hepatotoxicant and liver carcinogen in rodents. However, short-term tests for genotoxicity of furan are inconclusive. The aim of this study was to assess the potential of furan to covalently bind to DNA, and to assess furan genotoxicity in rats in vivo.