GATA6 Deficiency Leads to Epithelial Barrier Dysfunction and Enhances Susceptibility to Gut Inflammation

Laudisi, Federica; Stolfi, Carmine; Bevivino, Gerolamo; Maresca, Claudia; Franzè, Eleonora; Troncone, Edoardo; Lolli, Elisabetta; Marafini, Irene; Pietrucci, Daniele; Teofani, Adelaide; Di Grazia, Antonio; Di Fusco, Davide; Colantoni, Alfredo; Ortenzi, Angela; Desideri, Alessandro; Monteleone, Ivan; Monteleone, Giovanni

doi:10.1093/ecco-jcc/jjab145

GATA6 Deficiency Leads to Epithelial Barrier Dysfunction and Enhances Susceptibility to Gut Inflammation

Author(s)

Laudisi, Federica

Stolfi, Carmine

Bevivino, Gerolamo

Maresca, Claudia

Franzè, Eleonora

more

Date Issued

2022

Type

article

Volume

16

Issue

2

Start Page

301

End Page

311

DOI

10.1093/ecco-jcc/jjab145

Journal

JOURNAL OF CROHN'S AND COLITIS

Abstract

Intestinal barrier dysfunction is a hallmark of inflammatory bowel diseases [IBD], but the mechanisms that lead to such a defect are not fully understood. This study was aimed at characterising the factors involved in the defective barrier function in IBD.

Handle

http://hdl.handle.net/2067/51086