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  5. HPC-REDItools: a novel HPC-aware tool for improved large scale RNA-editing analysis

HPC-REDItools: a novel HPC-aware tool for improved large scale RNA-editing analysis

Author(s)
Flati, Tiziano
Gioiosa, Silvia
Spallanzani, Nicola
Tagliaferri, Ilario
Diroma, Maria Angela
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Date Issued
2020
Type
article
Volume
21
Issue
Suppl 10
Start Page
353
DOI
10.1186/s12859-020-03562-x
Journal
BMC BIOINFORMATICS  
Abstract
RNA editing is a widespread co-/post-transcriptional mechanism that alters primary RNA sequences through the modification of specific nucleotides and it can increase both the transcriptome and proteome diversity. The automatic detection of RNA-editing from RNA-seq data is computational intensive and limited to small data sets, thus preventing a reliable genome-wide characterisation of such process.
Handle
http://hdl.handle.net/2067/52941
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