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  5. Gut microbiota dysbiosis in Parkinson disease: A systematic review and pooled analysis

Gut microbiota dysbiosis in Parkinson disease: A systematic review and pooled analysis

Author(s)
Kleine Bardenhorst, Sven
Cereda, Emanuele
Severgnini, Marco
Barichella, Michela
Pezzoli, Gianni
more
Date Issued
2023
Type
article
Volume
30
Issue
11
Start Page
3581
End Page
3594
DOI
10.1111/ene.15671
Journal
EUROPEAN JOURNAL OF NEUROLOGY  
Abstract
The role of the gut microbiome in the pathogenesis of Parkinson disease (PD) is under intense investigation, and the results presented are still very heterogeneous. These discrepancies arise not only from the highly heterogeneous pathology of PD, but also from widely varying methodologies at all stages of the workflow, from sampling to final statistical analysis. The aim of the present work is to harmonize the workflow across studies to reduce the methodological heterogeneity and to perform a pooled analysis to account for other sources of heterogeneity.
Handle
http://hdl.handle.net/2067/51089
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2023_01_EJN_Bardenhorst_compressed.pdf

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2.38 MB

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57d66996b1cc60906f6a06ac471ea068

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