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Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/2183

Title: Intestinal T cells of Dicentrarchus labrax (L.): gene expression and functional studies
Authors: Picchietti, Simona
Guerra, Laura
Bertoni, Fabrizio
Randelli, Elisa
Belardinelli, Maria Cristina
Buonocore, Francesco
Rombout, Jan
Scapigliati, Giuseppe
Abelli, Luigi
Keywords: Fish Immunology
Evolution of immune system
GALT
Thymus
RNA in situ hybridization
Real-time PCR
Cytotoxic T cells
Dicentrarchus labrax
Issue Date: 2011
Publisher: Elsevier
Citation: Picchietti, S. et al. 2011. Intestinal T cells of Dicentrarchus labrax (L.): gene expression and functional studies. "Fish & Shellfish Immunology" 30 (2): 609-617
Abstract: Cellular and molecular data have evidenced a gut-associated lymphoid tissue in a variety of teleost species, abundantly containing T cells, whose origin, selection and functions are still unclear. This study reports CD4, CD8-α, MHCI-α, MHCII-β, rag-1 and TCR-β gene transcription along the intestine (anterior, middle and posterior segments) and in the thymus of one year-old Dicentrarchus labrax (L.). Real-time PCR findings depicted a main role of the thymus in T cell development, but also rag-1
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Description: L'articolo è disponibile sul sito dell'editore http://www.sciencedirect.com/
DOI: 10.1016/j.fsi.2010.12.006
URI: http://hdl.handle.net/2067/2183
ISSN: 1050-4648
Appears in Collections:DISA - Archivio della produzione scientifica

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