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Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/2069

Title: Zinc deficiency suppresses the development of oral tolerance in rats
Authors: Finamore, Alberto
Roselli, Marianna
Merendino, Nicolò
Nobili, Fabio
Vignolini, Francesco
Mengheri, Elena
Keywords: Zinc deficiency
Oral tolerance
Intestine
Cytokines
Rats
Issue Date: 2003
Publisher: American Society for Nutritional Sciences
Citation: Finamore, A. et al. 2003. Zinc deficiency suppresses the development of oral tolerance in rats. "Journal of nutrition" 133 (1): 191-198
Abstract: Oral tolerance is a specific immune unresponsiveness to food antigens to prevent hypersensitivity reactions. We investigated whether zinc deficiency affects oral tolerance. Rats were fed a control (C) or zincdeficient (ZD) diet, or pair-fed (PF) to ZD rats for 28 d. Beginning on d 7, rats were administered ovalbumin (OVA) orally to induce tolerance, or PBS 3 times/wk, and were then immunized by OVA injection. The proliferation of mesenteric lymph node (MLN) and spleen lymphocytes after in vitro
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Description: L'articolo è disponibile sul sito dell'editore http://jn.nutrition.org
URI: http://hdl.handle.net/2067/2069
ISSN: 0022-3166
Appears in Collections:DECOS - Archivio della produzione scientifica

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