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Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/1844

Title: Comparison among plasma-derived clotting Factor VIII by using
Authors: Timperio, Anna Maria
Gevi, Federica
Grazzini, Giuliano
Vaglio, Stefania
Zolla, Lello
Keywords: Contaminants
Mass spectrometry
SDS-PAGE
Haemophilia A
Plasma
Issue Date: 2010
Publisher: Italian Society of Transfusion Medicine and Immunohaematology (SIMTI)
Citation: Timperio, A. M. et al. 2010. Comparison among plasma-derived clotting factor VIII by using monodimensional gel electrophoresis and mass spectrometry. "Blood Transfusion" 8(suppl. 3): s98-s104
Abstract: Background. Deficiency or dysfunction of coagulation factor VIII (FVIII) is the underlying cause of haemophilia A. Haemophilic patients are at present treated with plasma-derived FVIII (pdFVIII) or recombinant FVIII (rFVIII) in order to correct their clotting deficiency. pdFVIII concentrates are exclusively produced from human plasma upon pooling from multiple donors. It is not know whether the presence of excess of other plasma proteins, in addition to von Willebrand factor, could stimulat
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Description: L'articolo è disponibile sul sito dell'editore http://www.bloodtransfusion.it
DOI: 10.2450/2010.016S
URI: http://hdl.handle.net/2067/1844
ISSN: 1723-2007
Appears in Collections:DISA - Archivio della produzione scientifica

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