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Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/1802

Title: Heat shock impairs DNA synthesis and down-regulates gene expression for leptin and Ob-Rb receptor in concanavalin A-stimulated bovine peripheral blood mononuclear cells
Authors: Lacetera, Nicola
Bernabucci, Umberto
Basiricò, Loredana
Morera, Patrizia
Nardone, Alessandro
Keywords: Heat stress
Stress da caldo
Gene expression
Espressione genica
Leptin
Leptina
Lymphocytes
Linfociti
Issue Date: 2009
Publisher: Elsevier
Citation: Lacetera, N. et al. 2009. Heat shock impairs DNA synthesis and down-regulates gene expression for leptin and Ob-Rb receptor in concanavalin A-stimulated bovine peripheral blood mononuclear cells. "Veterinary Immunology and Immunopathology" 127: 190-194
Abstract: This study verified whether leptin or its long isoform receptor (Ob-Rb) genes are expressed in proliferating lymphocytes from bovine species, and whether their expression changes with increased temperatures. Peripheral blood mononuclear cells (PBMC) from five Holstein cows were incubated in the presence of concanavalin A, and alternatively subjected for 65 h to each of the following treatments (T): 39 8C continuously (T39) or three 13-h cycles at 40 (T40), 41 (T41) or 42 8C (T42), respectively
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Description: L’articolo è disponibile sul sito dell’editore http://www.sciencedirect.com/science/journal/01652427
DOI: 10.1016/j.vetimm.2008.09.020
URI: http://hdl.handle.net/2067/1802
ISSN: 0165-2427
Appears in Collections:DiPA - Archivio della produzione scientifica

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