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|Title: ||Distribution of camptothecin-induced breakpoints in Chinese hamster cells treated in late S and G2 phases of the cell cycle.|
|Authors: ||Bassi, Loredana|
Natarajan, Adayapalam T.
|Issue Date: ||1998|
|Publisher: ||Oxford University Press|
|Citation: ||Bassi, L. et al. 1998. Distribution of camptothecin-induced breakpoints in Chinese hamster cells treated in late S and G2 phases of the cell cycle. "Mutagenesis" 13: 257-261|
|Abstract: ||The distribution of camptothecin (CPT)-induced break points in late S or G2 phase of the cell cycle observed in Chinese hamster chromosomes was analysed in 400 metaphases. Contrary to expectation, they were not localized in the heterochromatic regions, suggesting that these chromatid-type aberrations arise by a mechanism which does not involve collision of the CPT-trapped 'cleavable complex' with the replication fork. Since many break points mapped more frequently to light bands (DAPI negative) |
|Description: ||L'articolo è disponibile sul sito dell'editore: http://www.oxfordjournals.org|
|Appears in Collections:||DABAC - Archivio della produzione scientifica|
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