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Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/1717

Title: Lack of effect of caffeine post-treatment on X-rays chromosomal aberrations in Werner's syndrome lymphoblastoid cell lines: A Preliminary Report
Authors: Franchitto, Annapaola
Proietti De Santis, Luca
Pichierri, Pietro
Keywords: Werner's syndrome
Sindrome di Werner
hydroxyurea
Idrossiurea
G2 phase
Fase G2
Issue Date: 1999
Publisher: Informa Healthcare
Citation: Franchitto A., Proietti De Santis L., PIchierri P. 1999. Lack of effect of caffeine post-treatment on X-rays chromosomal aberrations in Werner's syndrome lymphoblastoid cell lines: A Preliminary Report. "International Journal of Radiation Biology". 75: 1349-1355
Abstract: PURPOSE: To investigate whether in Werner's syndrome cells the G2 phase of the cell cycle has some abnormal response to post-treatment with agents such as caffeine and hydroxyurea known to interfere with cellular response to DNA damage. MATERIALS AND METHODS: Two Werner's syndrome lymphoblastoid cell lines (KO375 and DJG) and the normal cell line SNW646 were exposed to 50 cGy of X-rays or mitomycin-C and posttreated with caffeine or hydroxyurea in the G2 phase of the cell cycle. RESULTS: H
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Description: L'articolo è disponibile sul sito dell'editore: http://informahealthcare.com
URI: http://hdl.handle.net/2067/1717
ISSN: 0955-3002
Appears in Collections:DABAC - Archivio della produzione scientifica

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