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Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/1707

Title: Enhancement of genetic instability in human B cells by Epstein-Barr virus latent infection
Authors: Giselico, Luigi
Carloni, Manuela
Palitti, Fabrizio
Mosesso, Pasquale
Alfonsi, Alberto Maria
Gualandi, Giampiero
Issue Date: 2001
Publisher: Oxford University Press
Citation: Gualandi, G. et al. 2001. Enhancement of genetic instability in human B cells by Epstein-Barr virus latent infection. "Mutagenesis" 16(3): 203-208
Abstract: The level of genetic instability, as assessed by micronucleus (MN) formation, was higher in Epstein-Barr virus (EBV)-converted B-cell lines with one copy of the EBV genome integrated in each cell than in the parental, EBV-negative, B lymphoma cells. MN induced by EBV latency, as analysed by in situ hybridization, contained mainly centromeric regions, indicating that the presence of EBV affects the segregation of entire chromosomes. The instability was inhibited by treatment with antioxidants. Fl
Description: L'articolo è disponibile sul sito dell'editore: http://mutage.oxfordjournals.org/
DOI: 10.1093/mutage/16.3.203
URI: http://hdl.handle.net/2067/1707
ISSN: 0267-8357
Appears in Collections:DABAC - Archivio della produzione scientifica

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