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Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/1681

Title: Evolution of cell-mediated immune defences: cloning and structural characterisation of the T cell receptor beta chain from the icefish Chionodraco hamatus (Perciformes: Channichthyidae)
Authors: Buonocore, Francesco
Randelli, Elisa
Viviana, Scala
Belardinelli, Maria Cristina
Casani, Daniela
Facchiano, Angelo M.
Costantini, Susan
Scapigliati, Giuseppe
Keywords: Fish Immunology
Molecular Biology and Evolution
Icefish
Chionodraco hamatus
T-cell receptor
Cloning
Real time PCR
3D structure
Issue Date: 2009
Publisher: Taylor & Francis
Citation: Buonocore, F. et al. 2009. Evolution of cell-mediated immune defences: cloning and structural characterisation of the T cell receptor beta chain from the icefish Chionodraco hamatus (Perciformes: Channichthyidae). "Italian Journal of Zoology" 76(3): 258-268
Abstract: Studies on the immune defence system of Antarctic fishes are of interest to investigate the presence of evolutionary adaptations to low temperature seawater. In the present paper, primers designed to conserved regions of TR , the antigen receptor expressed by T lymphocytes and mediator of main adaptive immune responses, were used for the homology cloning of the icefish Chionodraco hamatus TR  chain cDNA. The full length cDNA consists of 1219 nucleotides that translates in a single reading fr
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Description: L'articolo è disponibile sul sito dell'editore http://www.tandfonline.com/
DOI: 10.1080/11250000802364632
URI: http://hdl.handle.net/2067/1681
ISSN: 1125-0003
Appears in Collections:DISA - Archivio della produzione scientifica

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