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Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/1485

Title: Involvement of the cAMP-dependent pathway in the reduction of epileptiform bursting caused by somatostatin in the mouse hippocampus
Authors: Ristori, Chiara
Cammalleri, Maurizio
Martini, Davide
Pavan, Barbara
Liu, Yanqiang
Casini, Giovanni
Dal Monte, Massimo
Bagnoli, Paola
Keywords: Transduction pathway
Epilepsy
Hippocampal slices
PKA modulation
Electrophysiological recordings
Issue Date: 2008
Publisher: Springer Verlag
Citation: Ristori, C. 2008. Involvement of the cAMP-dependent pathway in the reduction of epileptiform bursting caused by somatostatin in the mouse hippocampus. "Naunyn-Schmiedeberg's Archives of Pharmacology" 378(6):563-577
Abstract: The cAMP pathway is major signal transduction system involved in hippocampal neurotransmission. Recently, the peptide somatostatin-14 (SRIF) has emerged as a key signal that, by activating its receptors, inhibits epileptiform bursting in the mouse hippocampus. Little is known on transduction mechanisms which may mediate SRIF function in native cell/tissues. Using a well established model of epileptiform activity induced by Mg2+-free medium with 4-aminopyridine (0 Mg2+⁄4-AP) in mouse hippocampal
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Description: L'articolo è disponibile sul sito dell'editore http://www.springerlink.com
DOI: 10.1007/s00210-008-0338-z
URI: http://hdl.handle.net/2067/1485
ISSN: 0028-1298
Appears in Collections:DISA - Archivio della produzione scientifica

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