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Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/1475

Title: Mapping of the full length and the truncated interleukin-18 receptor alpha transcripts in the mouse brain
Authors: Alboni, Silvia
Cervia, Davide
Ross, Brendon
Montanari, Claudia
Sanchez-Gonzales, Alejandro
Sanchez-Alavez, Manuel
Garibaldi-Marcondes, Maria Cecilia
De Vries, David
Sugama, Shuei
Brunello, Nicoletta
Blom, Joan
Tascedda, Fabio
Conti, Bruno
Keywords: Interleukin
Receptor
IL-18
IL-18R
Isoform
Brain
Issue Date: 2009
Publisher: Elsevier
Citation: Alboni, S. et al. 2009. Mapping of the full length and the truncated interleukin-18 receptor alpha in the mouse brain. "Journal of Neuroimmunology" 214(1-2): 43-54
Abstract: The cytokine IL-18 acts on the CNS both in physiological and pathological conditions. Its action occurs through the heterodimeric receptor IL-18Rα\β. To better understand IL-18 central effects, we investigated in the mouse brain the distribution of two IL-18Rα transcripts, a full length and an isoform lacking the intracellular domain hypothesized to be a decoy receptor. Both isoforms were expressed in neurons throughout the brain primarily with overlapping distribution but also with some unique
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Description: L'articolo è disponibile sul sito dell'editore http://www.sciencedirect.com/
DOI: 10.1016/j.jneuroim.2009.06.016
URI: http://hdl.handle.net/2067/1475
ISSN: 0165-5728
Appears in Collections:DISA - Archivio della produzione scientifica

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