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Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/1464

Title: An update on somatostatin receptor signaling in native systems and new insights on their pathophysiology
Authors: Cervia, Davide
Bagnoli, Paola
Keywords: Endogenous receptor
G protein
Transduction pathway
Somatotropinoma
Nervous system disease
Issue Date: 2007
Publisher: Elsevier
Citation: Cervia, D., Bagnoli, P. 2007. An update on somatostatin receptor signaling in native systems and new insights on their pathophysiology. "Pharmacology & Therapeutics" 116(2): 322-341
Abstract: The peptide somatostatin (SRIF) has important physiological effects (mostly inhibitory) which have formed the basis for the clinical use of SRIF compounds. SRIF binding to its five G-protein coupled receptors leads to the modulation of multiple transduction pathways. However, our current understanding of signalling exerted by receptors endogenously expressed in different cells/tissues reflects a rather complicated picture. On the other hand, the complexity of SRIF receptor signalling in patholog
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Description: L'articolo è disponibile sul sito dell'editore http://www.sciencedirect.com/
DOI: 10.1016/j.pharmthera.2007.06.010
URI: http://hdl.handle.net/2067/1464
ISSN: 0163-7258
Appears in Collections:DISA - Archivio della produzione scientifica

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