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Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/1453

Title: Somatostatin coupling to adenylyl cyclase activity in the mouse retina
Authors: Pavan, Barbara
Fiorini, Sara
Dal Monte, Massimo
Lunghi, Laura
Biondi, Carla
Bagnoli, Paola
Cervia, Davide
Keywords: Somatostatin
Receptor agonists and antagonists
Transduction pathways
G proteins
Knockout retina
Issue Date: 2004
Publisher: Springer Verlag
Citation: Pavan, B. et al. 2004. Somatostatin coupling to adenylyl cyclase activity in the mouse retina. "Naunyn-Schmiedeberg's Archives of Pharmacology" 370(2):91-98
Abstract: The peptide somatostatin-14 (SRIF) acts in the mammalian retina through its distinct receptors (sst1-5). Scarce information is available on SRIF function in the retina, including the elucidation of transduction pathways mediating SRIF action. We have investigated SRIF and SRIF receptor modulation of adenylyl cyclase (AC) activity in both wild type (WT) retinas and sst1 or sst2 knock-out (KO) retinas which are known to over-express sst2 or sst1 receptors, respectively. In WT retinas, application
Description: L'articolo è disponibile sul sito dell'editore http://www.springerlink.com/
DOI: 10.1007/s00210-004-0950-5
URI: http://hdl.handle.net/2067/1453
ISSN: 0028-1298
Appears in Collections:DISA - Archivio della produzione scientifica

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