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Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/1442

Title: Localization and function of GABA transporter 1 in the retina
Authors: Casini, Giovanni
Keywords: Neurotransmitter transporter
Horizontal cells
Amacrine cells
Ganglion cells
Müller cells
GABA receptors
GABA uptake
Reversed transport
Retinal development
Issue Date: 2008
Publisher: The Humana Press Inc.
Citation: Casini, G. 2008. Localization and function of GABA transporter 1 in the retina. In: Tombran-Tink, j., Barnstable, C.j. (a cura di). Ocular Transporters in Diseases and Drug Delivery. Totowa, NJ, The Humana Press Inc., pp. 293-313
Abstract: Plasma membrane transporters, located in the presynaptic terminal and/or surrounding glial cells, terminate synaptic transmission by operating rapid, high affinity uptake of the neurotransmitter from the synaptic cleft. Pharmacological blockade of transporters increases extracellular neurotransmitter levels and prolongs transmitter exposure to the receptors. GABA transporters (GATs) belong to the Na+ and Cl--dependent transporter family. Four GATs have been isolated and cloned in mammals. Of the
URI: http://hdl.handle.net/2067/1442
ISBN: 1588299589
Appears in Collections:DISA - Archivio della produzione scientifica

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