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Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/1349

Title: Potassium Bromate but not X-ray cause unexpectedly elevated levels of DNA breakage similar to those induced by ultraviolet light in Cockayne syndrome (CS-B) fibroblast
Authors: Mosesso, Pasquale
Penna, Sabrina
Pepe, Gaetano
Lorenti Garcia, Claudia
Palitti, Fabrizio
Keywords: DNA
Potassium bromate
Cockayne syndrome
Breakage
Fibroblast
Issue Date: 2004
Publisher: Karger
Citation: Mosesso, P. et al. 2004. Potassium Bromate but not X-ray cause unexpectedly elevated levels of DNA breakage similar to those induced by ultraviolet light in Cockayne syndrome (CS-B) fibroblast. "Cytogenetic and Genome Research" 104(1-4): 178-181.
Abstract: It has been previously reported that the elevated accumulation of repair incision intermediates in cells from patients with combined characteristics of xeroderma pigmentosum complementation group D (XP-D) and Cockayne syndrome (CS) XP-D/CS fibroblasts following UV irradiation is caused by an "uncontrolled" incision of undamaged genomic DNA induced by UV-DNA-lesions which apparently are not removed. This could be an explanation for the extreme sensitivity of these cells to UV light. In the presen
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Description: L'articolo é disponibile sul sito dell'editore: http://www.karger.com
DOI: 10.1159/000077485
URI: http://hdl.handle.net/2067/1349
ISSN: 1424-8581
Appears in Collections:DABAC - Archivio della produzione scientifica

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