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Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/1348

Title: Relationship between chromatin structure, DNA damage and repair following X-irradiation of human lymphocytes
Authors: Mosesso, Pasquale
Palitti, Fabrizio
Pepe, Gaetano
Piñero, Joaquin
Bellacima, Raffaela
Ahnström, Gunnar
Natarajan, Adayapalam T.
Keywords: FISH-Comet assay
DNA repair
Heterochromatin
CpG islands
DMSO
Radical scavengers
Exchange aberrations and chromatin architecture
Saggio del FISH-Comet
Riparazione del Danno al DNA
Eterocromatina
Isole CpG
DMSO
Neutralizzatore di radicali liberi
Scambi cromosomici ed architettura della cromatina
Issue Date: 2010
Publisher: Elsevier
Citation: Mosesso, P. et al. 2010. Relationship between chromatin structure, DNA damage and repair following X-irradiation of human lymphocytes. "Mutation Research. Genetic Toxicology and Environmental Mutagenesis" 701(1): 86-91
Abstract: Earlier studies using the technique of premature chromosome condensation (PCC) have shown that in human lymphocytes, exchange type of aberrations are formed immediately following low doses (<2 Gy) of X-rays, whereas at higher doses these aberrations increase with the duration of recovery. This reflects the relative roles of slow and fast repair in the formation of exchange aberrations. The underlying basis for slow and fast repairing components of the DNA repair may be related to differential lo
...more
Description: L'articolo é disponibile sul sito dell'editore: http://www.sciencedirect.com
URI: http://hdl.handle.net/2067/1348
ISSN: 1383-5718
Appears in Collections:DABAC - Archivio della produzione scientifica

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