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Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/1346

Title: In vitro cytogenetic results supporting a DNA nonreactive mechanism for ochratoxin A, potentially relevant for its carcinogenicity
Authors: Mosesso, Pasquale
Cinelli, Serena
Piñero, Joaquin
Bellacima, Raffaela
Pepe, Gaetano
Keywords: Genotoxicity of OTA
Mycotoxins
Genotossicità del'OTA
Micotossine
Issue Date: 2008
Publisher: American Chemical Society
Citation: Mosesso, P. et al. 2008. In vitro cytogenetic results supporting a DNA nonreactive mechanism for ochratoxin A, potentially relevant for its carcinogenicity. "Chemical Research in Toxicology" 21(6): 1235-1243
Abstract: Ochratoxin A (OTA) is a widespread mycotoxin of cereals and many agricultural products and causes high incidences of renal tumors in rodents. Although its carcinogenic properties have been known since the eighties, the precise mechanism of action is still relatively undefined. At present, increasing evidence suggests that OTA does not act with a direct genotoxic mechanism, opposed to other previous evidence where the formation of DNA adducts by 32P-postlabeling was observed. The genotoxic ac
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Description: The present paper is dedicated to Prof. A. T. Natarajan on the occasion of his 80th birthday.
L'articolo è disponibile sul sito dell'editore: http://pubs.acs.org/
DOI: 10.1021/tx800029f
URI: http://hdl.handle.net/2067/1346
ISSN: 0893-228X
Appears in Collections:DABAC - Archivio della produzione scientifica

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