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Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/1331

Title: Cellular thermotolerance is associated with heat shock protein 70.1 genetic polymorphisms in Holstein lactating cows
Authors: Basiricò, Loredana
Morera, Patrizia
Primi, Valentina
Lacetera, Nicola
Nardone, Alessandro
Bernabucci, Umberto
Keywords: Hsp70.1
Gene polymorphism
Polimorfismo genetico
Peripheral blood mononuclear cells
Linfociti
Thermotolerance
Termotolleranza
Dairy cows
Vacche da latte
Issue Date: 2011
Publisher: Springer
Citation: Basiricò, L. et al. 2011. Cellular thermotolerance is associated with heat shock protein 70.1 genetic polymorphisms in Holstein lactating cows. "Cell stress and chaperones" 16 (4): 441-448
Abstract: The present study aimed to investigate the association between inducible Hsp70.1 single nucleotide polymorphisms (SNPs) and heat shock (HS) response of peripheral blood mononuclear cells (PBMC) in dairy cows. Exposure to HS differently affected cell viability and gene and protein expression of Hsp70.1 in the selected genotypes. These results indicate that the presence of SNPs (C/- and G/T) in the 5′-UTR region of inducible Hsp70.1 ameliorates HS response and tolerance to heat of bovine PBMC. The
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Description: L'articolo è disponibile sul sito dell'editore: http://link.springer.com/journal/12192
DOI: 10.1007/s12192-011-0257-7
URI: http://hdl.handle.net/2067/1331
ISSN: 1355-8145
Appears in Collections:DiPA - Archivio della produzione scientifica

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