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Please use this identifier to cite or link to this item: http://hdl.handle.net/2067/125

Title: Signatures of selection? Patterns of microsatellite diversity on a chromosome containing a selected locus
Authors: Wiener, Pamela
Burton, David
Ajmone-Marsan, Paolo
Dunner, Susana
Valentini, Alessio
Williams, John L.
Keywords: Linkage disequilibrium
Hitchhiking
Myostatin
Double muscling
Belgian blue cattle
Issue Date: 2003
Publisher: Nature Publishing Group
Citation: Wiener, P., Burton, D., Ajmone-Marsan, P., Dunner, S., Mommens, G., Nijman, I.J., Rodellar, C., Valentini, A., Williams, J.L., 2003. Signatures of selection? Patterns of microsattelite diversity on a chromosome containing a selected locus. Heredity. 90, 350–358.
Abstract: This paper explores patterns of genetic diversity near a locus known to have been under selection. The myostatin gene (GDF-8) has been shown to be associated with double muscling, a phenotype selected for in a number of cattle breeds. We examined population genetic parameters for microsatellite loci at varying distances from GDF-8 in double-muscled (DM) and non-double-muscled (non-DM) cattle breeds in order to assess patterns of diversity. A theoretical analysis was also performed to predict the
...more
URI: http://hdl.handle.net/2067/125
ISSN: 0022-1503
Appears in Collections:DiPA - Archivio della produzione scientifica

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