http://http://dspace.unitus.it:80 The DSpace digital repository system captures, stores, indexes, preserves, and distributes digital research material. Wed, 19 Jun 2013 20:44:17 GMT 2013-06-19T20:44:17Z http://hdl.handle.net/2067/1734 Title: New lipophilic piceatannol derivatives exhibiting antioxidant activity prepared by aromatic hydroxylation with 2-iodoxybenzoic acid (IBX) Authors: Bernini, Roberta; Barontini, Maurizio; Spatafora, Carmela Abstract: Piceatannol (E-3,5,3’,4’ tetrahydroxystilbene) is a phytoalexin synthesized in grapes in response to stress conditions. It exhibits strong antioxidant and antileukaemic activities due to the presence of the catechol moiety. To modify some physical properties like solubility, and miscibility in non-aqueous media some new previously unreported piceatannol derivatives having lipophilic chains on the A-ring were prepared in good yields by a simple and efficient procedure. The key step was a chemo- and regioselective aromatic hydroxylation with 2-iodoxybenzoic acid (IBX). The new compounds showed antioxidant activity and seemed promising for possible applications as multifunctional emulsifiers in food, cosmetic and pharmaceutical fields. Description: L'articolo è disponibile sul sito dell'editore: http://www.mdpi.com Wed, 31 Dec 2008 23:00:00 GMT http://hdl.handle.net/2067/1734 2008-12-31T23:00:00Z