The DSpace digital repository system captures, stores, indexes, preserves, and distributes digital research material. http://http://dspace.unitus.it:80 2013-06-20T11:53:14Z 2013-06-20T11:53:14Z Pariset, Lorraine Cuteri, Antonella Ligda, Christina Ajmone-Marsan, Paolo Valentini, Alessio Econogene Consortium http://hdl.handle.net/2067/1883 2011-05-20T21:43:47Z 2011-04-05T22:00:00Z

Title: Geographical patterning of sixteen goat breeds from Italy, Albani a and Greece assessed by Single Nucleotide Polymorphisms Authors: Pariset, Lorraine; Cuteri, Antonella; Ligda, Christina; Ajmone-Marsan, Paolo; Valentini, Alessio; Econogene Consortium Abstract: Background: SNP data of goats of three Mediterranean countries were used for population studies and reconstruction of geographical patterning. 496 individuals belonging to Italian, Albanian and Greek breeds were genotyped to assess the basic population parameters. Results: A total of 26 SNPs were used, for a total of 12,896 genotypes assayed. Statistical analysis revealed that breeds are not so similar in terms of genetic variability, as reported in studies performed using different markers. The Mantel test showed a strongly significant correlation between genetic and geographic distance. Also, PCA analysis revealed that breeds are grouped according to geographical origin, with the exception of the Greek Skopelos breed. Conclusion: Our data point out that the use of SNP markers to analyze a wider breed sample could help in understanding the recent evolutionary history of domestic goats. We found correlation between genetic diversity and geographic distance. Also PCA analysis shows that the breeds are well differentiated, with good correspondence to geographical locations, thus confirming the correlation between geographical and genetic distances. This suggests that migration history of the species played a pivotal role in the present-day structure of the breeds and a scenario in which coastal routes were easier for migrating in comparison with inland routes. A westward coastal route to Italy through Greece could have led to gene flow along the Northern Mediterranean.

2011-04-05T22:00:00Z Naderi, Saeid Rezaei, Hamid-Reza Taberlet, Pierre Zundel, Stéphanie Rafat, Seyed-Abbas Naghash, Hamid-Reza El- Barody, Mohamed A. A. Ertugrul, Okan Pompanon, François Abo-Shehada, Mahamoud Ajmone-Marsan, Paolo Al Tarrayrah, Jamil Baret, Philippe Baumung, Roswitha Beja-Pereira, Albano Bertaglia, Marco Bordonaro, Salvatore Bruford, Mike Caloz, Régis Canali, Gabriele Canon, Javier Cappuccio, Irene Carta, Antonello Cicogna, Mario Cortes, Oscar Crepaldi, Paola Dalamitra, Stella Daniela, Krugmann Dobi, Petrit Dominik, Popielarczyk Dunner, Susana D'Urso, Giuseppe England, Phillip Erhardt, Georg Prinzenberg, Eva-Maria Ibeagha-Awemu, Eveline Strzelec, Ewa Fadlaoui, Aziz Fornarelli, Francesca Garcia, David Georgoudis, Andreas Lühken, Gesine Giovenzana, Stefano Gutscher, Katja Hewitt, Godfrey Hoda, Anila Brandt, Horst Istvan, Anton Juma, Gabriela Joost, Stéphane Jones, Sam Karetsou, Katerina Kliambas, Georgios Koban, Evren Kutita, Olga Fesus, Lazlo Lenstra, Johannes A. Ligda, Christina Lipsky, Shirin Luikart, Gordon Glowatzki, Marie-Louise Marilli, Marta Marletta, Donata Milanesi, Elisabetta Negrini, Riccardo Nijman, Isaäc J. Obexer-Ruff, Gabriela Papachristoforou, Christos Pariset, Lorraine Pellecchia, Marco Peter, Christina Perez, Trinidad Pilla, Fabio D'Andrea, Mariasilvia Niznikowski, Roman Roosen, Jutta Scarpa, Riccardo Sechi, Tiziana Taylor, Martin Togan, Inci Trommetter, Michel Valentini, Alessio Van Cann, Lisette M. Vlaic, Augustin Wiskin, Louise Zundel, Stéphanie http://hdl.handle.net/2067/1922 2011-05-20T22:30:41Z 2011-04-13T22:00:00Z

Title: Large-Scale Mitochondrial DNA Analysis of the Domestic Goat Reveals Six Haplogroups with High Diversity Authors: Naderi, Saeid; Rezaei, Hamid-Reza; Taberlet, Pierre; Zundel, Stéphanie; Rafat, Seyed-Abbas; Naghash, Hamid-Reza; El- Barody, Mohamed A. A.; Ertugrul, Okan; Pompanon, François; Abo-Shehada, Mahamoud; Ajmone-Marsan, Paolo; Al Tarrayrah, Jamil; Baret, Philippe; Baumung, Roswitha; Beja-Pereira, Albano; Bertaglia, Marco; Bordonaro, Salvatore; Bruford, Mike; Caloz, Régis; Canali, Gabriele; Canon, Javier; Cappuccio, Irene; Carta, Antonello; Cicogna, Mario; Cortes, Oscar; Crepaldi, Paola; Dalamitra, Stella; Daniela, Krugmann; Dobi, Petrit; Dominik, Popielarczyk; Dunner, Susana; D'Urso, Giuseppe; England, Phillip; Erhardt, Georg; Prinzenberg, Eva-Maria; Ibeagha-Awemu, Eveline; Strzelec, Ewa; Fadlaoui, Aziz; Fornarelli, Francesca; Garcia, David; Georgoudis, Andreas; Lühken, Gesine; Giovenzana, Stefano; Gutscher, Katja; Hewitt, Godfrey; Hoda, Anila; Brandt, Horst; Istvan, Anton; Juma, Gabriela; Joost, Stéphane; Jones, Sam; Karetsou, Katerina; Kliambas, Georgios; Koban, Evren; Kutita, Olga; Fesus, Lazlo; Lenstra, Johannes A.; Ligda, Christina; Lipsky, Shirin; Luikart, Gordon; Glowatzki, Marie-Louise; Marilli, Marta; Marletta, Donata; Milanesi, Elisabetta; Negrini, Riccardo; Nijman, Isaäc J.; Obexer-Ruff, Gabriela; Papachristoforou, Christos; Pariset, Lorraine; Pellecchia, Marco; Peter, Christina; Perez, Trinidad; Pilla, Fabio; D'Andrea, Mariasilvia; Niznikowski, Roman; Roosen, Jutta; Scarpa, Riccardo; Sechi, Tiziana; Taylor, Martin; Togan, Inci; Trommetter, Michel; Valentini, Alessio; Van Cann, Lisette M.; Vlaic, Augustin; Wiskin, Louise; Zundel, Stéphanie Abstract: From the beginning of domestication, the transportation of domestic animals resulted in genetic and demographic processes that explain their present distribution and genetic structure. Thus studying the present genetic diversity helps to better understand the history of domestic species. Methodology/Principal Findings. The genetic diversity of domestic goats has been characterized with 2430 individuals from all over the old world, including 946 new individuals from regions poorly studied until now (mainly the Fertile Crescent). These individuals represented 1540 haplotypes for the HV segment of the mitochondrial DNA (mtDNA) control region. This large-scale study allowed the establishment of a clear nomenclature of the goat maternal haplogroups. Only five of the six previously defined groups of haplotypes were divergent enough to be considered as different haplogroups. Moreover a new mitochondrial group has been localized around the Fertile Crescent. All groups showed very high haplotype diversity. Most of this diversity was distributed among groups and within geographic regions. The weak geographic structure may result from the worldwide distribution of the dominant A haplogroup (more than 90% of the individuals). The large-scale distribution of other haplogroups (except one), may be related to human migration. The recent fragmentation of local goat populations into discrete breeds is not detectable with mitochondrial markers. The estimation of demographic parameters from mismatch analyses showed that all groups had a recent demographic expansion corresponding roughly to the period when domestication took place. But even with a large data set it remains difficult to give relative dates of expansion for different haplogroups because of large confidence intervals Conclusions/Significance. We propose standard criteria for the definition of the different haplogroups based on the result of mismatch analysis and on the use of sequences of reference. Such a method could be also applied for clarifying the nomenclature of mitochondrial haplogroups in other domestic species.

2011-04-13T22:00:00Z